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A blister is a small pocket of fluid within the upper layers of the skin. Most blisters are filled with a clear fluid called serum.
A blister usually forms because the outer layer of the skin has become damaged. Fluid collects under the damaged layer of skin, cushioning the tissue underneath, protecting it from further damage and allowing it to heal.
Short periods of intense rubbing can cause a blister. Blisters are most common on the hands and feet, as these extremities are susceptible while walking, running, or performing repetitive motions.
Blisters form more easily on moist skin than on dry or soaked skin, and are more common in warm conditions.
Sometimes, the skin can blister when it comes into contact with a cosmetic, detergent, solvent or other chemical; this is known as contact dermatitis. Blisters can also develop as a result of an allergic reaction to an insect bite or sting.
Certain medical conditions like eczema called dyshidrosis can cause this condition.
Most blisters heal naturally and do not require medical attention. As new skin grows beneath the blister, the fluid contained within it will be slowly reabsorbed by the body and the skin on top will dry and peel off.
You should try to keep blisters intact and unbroken in order to avoid infection. Blisters that have become infected can be treated with prescription antibiotics. Blisters caused by a medical condition are treated by treating the underlying condition.
You can dust powder on the blistered area to keep them dry and aid in faster resolution.
ref:http://en.wikipedia.org/wiki/Blister