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Ovarian Cancer  (Expert Forum)
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Risks and post op treatment
Answered by
Annekathryn Goodman, M.D. - Gynecologic Cancers, Complex Gynecologic, Surgeries, Palliative Care, Acupuncture
Massachusetts General Hospital Cancer Center Boston - MA
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This forum is for questions and support regarding ovarian cancer issues, such as: Biopsy, Chemotherapy, Clinical Trials, Genetics, Hysterectomy,Immunotherapy, Ovarian Cancer Types, Radiation Therapy, Risk Factors, Screening, Staging, Surgery.

Risks and post op treatment

by sandysandy, Jun 17, 2008 04:00PM
Hi Dr. Goodman,

What are the OC risks for BRCA2 (not including the BRCA1 stats) over time?   (I am BRCA2)

Also, if I have my ovaries taken out at age 50, what will be the symptoms I will experience after an oopherectomy?  I have a regular cycle although the duration of my period is less (which occurred after removal of 5 uterine polyps a couple years ago.  Should I be given have low level HRT in a tapered fashion so I don't have mega symptoms after surgery?  Woudl HRT be a big deal for me since it would be lower than if I went through menopause.  Should I expect significant menopausal symptoms after surgery?   (Also, I've also had BC  SII ... 3.5 cm, no node or lymph vessel invasion .. 13 years prior with bi-lat mast and 6 CAF for treatment).

A couple of my sisters have had full hysterectomies and suffered afterwards with depression.  I see that as part of the post menopausal symptoms and I am worried about that as part of my post operative care and recovery.

by Annekathryn Goodman, M.D., Jul 07, 2008 10:09PM
Hi There,

risks for BRCA 2 are as follows:
-Average 45 percent lifetime risk for breast cancer (in females)
-6 percent lifetime risk for breast cancer (in males)
-Average 11 percent lifetime risk for ovarian cancer
-increased risk for other cancer types, such as pancreatic, prostate, laryngeal, stomach cancer, and melanoma

The consequence of removing the ovaries is early menopause. there is alot written about menopause. It is very individual.

Here is one nice site that you can look around in.

http://www.webmd.com/menopause/
best wishes
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